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ENDOGL1 Blocking Peptide | EXOG blocking peptide

ENDOGL1 Blocking Peptide

Gene Names
EXOG; ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2
Reactivity
Human
Applications
Blocking (BL)
Purity
>85%
Synonyms
ENDOGL1; ENDOGL1 Blocking Peptide; ENDOGL2; ENGL; Nuclease EXOG; mitochondrial; Endonuclease G-like 1; Endo G-like 1; EXOG blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
318
Applicable Applications for EXOG blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for EXOG blocking peptide
The peptide is used to block Anti-ENDOGL1 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,437 Da
NCBI Official Full Name
nuclease EXOG, mitochondrial isoform 2
NCBI Official Synonym Full Names
endo/exonuclease (5'-3'), endonuclease G-like
NCBI Official Symbol
EXOG
NCBI Official Synonym Symbols
ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2
NCBI Protein Information
nuclease EXOG, mitochondrial; endo G-like 1; endonuclease G-like 1; endonuclease G-like 2
UniProt Protein Name
Nuclease EXOG, mitochondrial
Protein Family
UniProt Gene Name
EXOG
UniProt Synonym Gene Names
ENDOGL1; ENDOGL2; ENGL; Endo G-like 1
UniProt Entry Name
EXOG_HUMAN

NCBI Description

This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]

Uniprot Description

ENDOGL1: Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity. Belongs to the DNA/RNA non-specific endonuclease family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.30.-; Deoxyribonuclease; Ribonuclease; Mitochondrial

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: nucleic acid binding; metal ion binding; endonuclease activity

Biological Process: DNA catabolic process, endonucleolytic

Research Articles on EXOG

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Product Notes

The EXOG exog (Catalog #AAA823804) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The ENDOGL1 Blocking Peptide reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ENDOGL1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the EXOG exog for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENDOGL1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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