Western Blot (WB)
(Western blot analysis of Basonuclin expression in HKE293T (A), Raw264.7 (B), PC12 (C) whole cell lysates.)
Rabbit Basonuclin Polyclonal Antibody | anti-BNC1 antibody
Anti-Basonuclin Antibody
Western Blot (WB)
(Western blot analysis of Basonuclin expression in HKE293T (A), Raw264.7 (B), PC12 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Basonuclin expression in HKE293T (A), Raw264.7 (B), PC12 (C) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. Alternative splicing of this gene results in multiple transcript variants, and multiple polyadenylation sites are indicated.[provided by RefSeq, Jul 2014]
Uniprot Description
basonuclin 1: Likely to be a transcription factor specific for squamous epithelium and for the constituent keratinocytes at a stage either prior to or at the very beginning of terminal differentiation. May play a role in the differentiation of spermatozoa and oocytes.
Protein type: C2H2-type zinc finger protein; Transcription factor
Chromosomal Location of Human Ortholog: 15q25.2
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase I promoter; epidermis development; wound healing; transcription, DNA-dependent; positive regulation of cell proliferation; chromosome organization and biogenesis; positive regulation of epithelial cell proliferation
Research Articles on BNC1
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Product Notes
The BNC1 bnc1 (Catalog #AAA822185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Basonuclin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Basonuclin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the BNC1 bnc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Basonuclin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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