BEX4 sirna

BEX4 siRNA (Human)

Cat. Num. AAA8212141

• Gene Names: BEX4; BEXL1
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: BEX4; BEX4 siRNA (Human); BEXL1; NADE3; Protein BEX4; BEX1-like protein 1; Brain-expressed X-linked protein 4; Nerve growth factor receptor-associated protein 3; BEX4 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: BEX4 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 120

• Applicable Applications for BEX4 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human BEX4 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for BEX4 sirna

siRNA to inhibit BEX4 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 122937245
• NCBI GeneID: 56271
• NCBI Accession #: NP_001073894.1
• NCBI GenBank Nucleotide #: NM_001080425.3
• UniProt Accession #: Q9NWD9
• Molecular Weight: 14,067 Da
• NCBI Official Full Name: protein BEX4
• NCBI Official Synonym Full Names: brain expressed, X-linked 4
• NCBI Official Symbol: BEX4
• NCBI Official Synonym Symbols: BEXL1
• NCBI Protein Information: protein BEX4
• UniProt Protein Name: Protein BEX4
• Protein Family: Protein
• UniProt Gene Name: BEX4
• UniProt Synonym Gene Names: BEXL1; NADE3
• UniProt Entry Name: BEX4_HUMAN

NCBI Description

This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

Uniprot Description

BEX4: a member of the brain expressed X-linked gene family. The proteins encoded by some of the other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

Chromosomal Location of Human Ortholog: Xq22.1-q22.3

Cellular Component: cytoplasm; nucleus