CDKN1C sirna
CDKN1C siRNA (Mouse)
NCBI and Uniprot Product Information
Uniprot Description
p57Kip2: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life. Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver. Belongs to the CDI family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Nuclear receptor co-regulator; Inhibitor; Cell cycle regulation
Cellular Component: nucleus
Molecular Function: cyclin-dependent protein kinase inhibitor activity; protein binding; protein kinase inhibitor activity
Biological Process: camera-type eye development; adrenal gland development; multicellular organism growth; regulation of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; cell cycle; uterus development; neuron maturation; negative regulation of phosphorylation; myeloid cell differentiation; kidney development; cell cycle arrest; skeletal development; aging; placenta development
Research Articles on CDKN1C
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Product Notes
The CDKN1C cdkn1c (Catalog #AAA8204989) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The CDKN1C siRNA (Mouse) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDKN1C can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the CDKN1C cdkn1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDKN1C, siRNA" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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