Rabbit anti-Human CSGALNACT1 Polyclonal Antibody | anti-CSGALNACT1 antibody
Anti-CSGALNACT1 Antibody
Western Blot (WB)
(Western blot analysis of CSGALNACT1 expression in MCF7 (A), K562 (B) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of CSGALNACT1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
Uniprot Description
ChGn: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174
Chromosomal Location of Human Ortholog: 8p21.3
Cellular Component: Golgi membrane; integral to Golgi membrane; intracellular
Molecular Function: glucuronosyltransferase activity; acetylgalactosaminyltransferase activity; metal ion binding; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; peptidoglycan glycosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Biological Process: nervous system development; anatomical structure morphogenesis; extracellular matrix organization and biogenesis; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; chondroitin sulfate proteoglycan biosynthetic process; cell recognition; pathogenesis; UDP-N-acetylgalactosamine metabolic process; chondroitin sulfate metabolic process; cell proliferation; UDP-glucuronate metabolic process; heparin biosynthetic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; cartilage development; proteoglycan biosynthetic process; carbohydrate metabolic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; endochondral ossification
Research Articles on CSGALNACT1
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Product Notes
The CSGALNACT1 csgalnact1 (Catalog #AAA820345) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CSGALNACT1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CSGALNACT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100). Researchers should empirically determine the suitability of the CSGALNACT1 csgalnact1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSGALNACT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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