Serpin A11 Recombinant Protein | SerpinA11 recombinant protein

Serpin A11 Protein, Mouse, Recombinant (His Tag)

Cat. Num. AAA8122740

• Gene Names: Serpina11; Gm895
• Purity: >94% as determined by SDS-PAGE
• Synonyms: Serpin A11; Serpin A11 Protein; Mouse; Recombinant (His Tag); Mouse SerpinA11 Protein (His Tag); Gm895 Protein; serpin peptidase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 11; SerpinA11 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >94% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Gly424

• Species: Mouse
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Gln 22
• Tag: C-His
• Protein Construction: A DNA sequence encoding the mouse SERPINA11 isoform 1 (NP_955018.2)(Met 1-Gly 424) was expressed, fused with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for SerpinA11 recombinant protein

Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1 serpins have been identified. Mouse Serpin A11, also known as SERPINA11, is a member of the serpin family.

References

Irving JA. et al., 2000, Genome Res. 10: 1845-64. Irving J. et al., 2002, Mol Biol Evol 19 (11): 1881-90. Forsyth, S. et al., 2003, Genomics 81: 336-345. Horvath, AJ. et al., 2004, J. Mol. Evol. 59: 488-497. Steenbakkers PJ. et al., 2008, Mycol. Res. 112 (Pt 8): 999-1006.

NCBI and Uniprot Product Information

• NCBI GI #: 261599046
• NCBI GeneID: 380780
• NCBI Accession #: NP_955018.2
• NCBI GenBank Nucleotide #: NM_199314.2
• UniProt Accession #: Q8CIE0
• Molecular Weight: 47,188 Da
• NCBI Official Full Name: serpin A11 isoform 1
• NCBI Official Synonym Full Names: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
• NCBI Official Symbol: Serpina11
• NCBI Official Synonym Symbols: Gm895
• NCBI Protein Information: serpin A11; serine (or cysteine) proteinase inhibitor, clade A, member 11; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
• UniProt Protein Name: Serpin A11
• Protein Family: Serpin
• UniProt Gene Name: Serpina11
• UniProt Synonym Gene Names: Gm895
• UniProt Entry Name: SPA11_MOUSE

Uniprot Description

SERPINA11: Belongs to the serpin family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; protease inhibitor activity

Biological Process: negative regulation of peptidase activity