Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS769457 (FRS2 antibody) at dilution of 1:50)
Rabbit FRS2 Polyclonal Antibody | anti-FRS2 antibody
FRS2 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS769457 (FRS2 antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS769457 (FRS2 antibody) at dilution of 1:50)
Western Blot (WB)
(MCF-7 cells were subjected to SDS PAGE followed by western blot with MBS769457 (FRS2 Antibody) at dilution of 1:1000)
Western Blot (WB)
(MCF-7 cells were subjected to SDS PAGE followed by western blot with MBS769457 (FRS2 Antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
Uniprot Description
FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: endosome; integral to plasma membrane; intercellular junction; membrane; plasma membrane
Molecular Function: 1-phosphatidylinositol-3-kinase activity; fibroblast growth factor receptor binding; insulin receptor binding; neurotrophin TRKA receptor binding; phosphatase activator activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; Ras guanyl-nucleotide exchange factor activity; transmembrane receptor protein tyrosine kinase adaptor protein activity
Biological Process: activation of MAPK activity; activation of MAPKK activity; determination of anterior/posterior axis, embryo; fibroblast growth factor receptor signaling pathway; forebrain development; G-protein coupled receptor protein signaling pathway; gastrulation with mouth forming second; induction of an organ; MAPKKK cascade; neuroblast proliferation; optic placode formation involved in camera-type eye; phosphoinositide phosphorylation; phosphoinositide-mediated signaling; positive regulation of GTPase activity; regulation of apoptosis; regulation of epithelial cell proliferation; regulation of phosphoinositide 3-kinase cascade; transmembrane receptor protein tyrosine phosphatase signaling pathway
Research Articles on FRS2
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Product Notes
The FRS2 frs2 (Catalog #AAA769457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FRS2 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FRS2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the FRS2 frs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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