Pigeon Capping Protein Muscle Z Line Beta ELISA Kit | CAPZbeta elisa kit
Pigeon Capping Protein Muscle Z Line Beta ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.
Subunit structure: Heterodimer of an alpha and a beta subunit. Component of the WASH complex
By similarity. Isoform 2 also is a component of dynactin complex from brain, which contains the actin-related protein ARP1. Ref.2
Subcellular location: Isoform 1: Cytoplasm › myofibril › sarcomere › Z line. Note: In cardiac muscle, isoform 1 is located at Z-disks of sarcomeres. Ref.2Isoform 2: Cytoplasm › myofibril › sarcomere › I band. Cytoplasm › cytoskeleton
By similarity. Note: In cardiac muscle, isoform 2 is located at sarcomere intercalated disks. Ref.2
Tissue specificity: Isoform 1 is detected in pectoral muscle, cardiac muscle and gizzard. Isoform 2 is detected in brain and liver (at protein level). Isoform 2 is the predominant isoform ofnonmuscle tissues and isoform 1 is the predominant isoform ofmuscle tissues. Ref.2
Sequence similarities: Belongs to the F-actin-capping protein beta subunit family.
Similar Products
Product Notes
The Pigeon CAPZbeta capzb (Catalog #AAA076829) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA076829 ELISA Kit recognizes Pigeon CAPZbeta. It is sometimes possible for the material contained within the vial of "Capping Protein Muscle Z Line Beta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
