Rabbit CISD1 Polyclonal Antibody | anti-CISD1 antibody

CISD1 Rabbit Polyclonal

Cat. Num. AAA767949

• Gene Names: CISD1; ZCD1; MDS029; C10orf70; mitoNEET
• Reactivity: Human, Mouse, Rat, Zebrafish
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Flow Cytometry, Functional Assay
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CISD1; Polyclonal Antibody; CISD1 Rabbit Polyclonal; anti-CISD1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Zebrafish
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 108

• Applicable Applications for anti-CISD1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Immunogen: CDGSH iron sulfur domain 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human heart using MBS767949 (mitoNEET,CISD1 antibody) at dilution of 1:100)

Testing Data

()

Western Blot (WB)

(mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS767949 (mitoNEET,CISD1 antibody) at dilution of 1:4000)

NCBI and Uniprot Product Information

• NCBI GI #: 8923930
• NCBI GeneID: 55847
• NCBI Accession #: NP_060934.1
• NCBI GenBank Nucleotide #: NM_018464.4
• Molecular Weight: 12,199 Da
• NCBI Official Full Name: CDGSH iron-sulfur domain-containing protein 1
• NCBI Official Synonym Full Names: CDGSH iron sulfur domain 1
• NCBI Official Symbol: CISD1
• NCBI Official Synonym Symbols: ZCD1; MDS029; C10orf70; mitoNEET
• NCBI Protein Information: CDGSH iron-sulfur domain-containing protein 1
• UniProt Protein Name: CDGSH iron-sulfur domain-containing protein 1
• Protein Family: CDGSH iron-sulfur domain-containing protein
• UniProt Gene Name: CISD1
• UniProt Synonym Gene Names: C10orf70; ZCD1
• UniProt Entry Name: CISD1_HUMAN

NCBI Description

This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]

Uniprot Description

ZCD1: Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family.

Protein type: Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 10q21.1

Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: 2 iron, 2 sulfur cluster binding; metal ion binding

Biological Process: regulation of cellular respiration