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MIRO2 recombinant protein

Recombinant Human MIRO2

Gene Names
RHOT2; RASL; ARHT2; MIRO2; MIRO-2; C16orf39
Applications
Western Blot, ELISA
Purity
Greater than 95% by SDS-PAGE gel analyses
Synonyms
MIRO2; Recombinant Human MIRO2; ARHT2; C16orf39; hMiro 2; MIRO 2; miro2; Mitochondrial Rho GTPase 2; RASL; RHOT2; MIRO2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95% by SDS-PAGE gel analyses
Form/Format
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Sequence Positions
392-541
Applicable Applications for MIRO2 recombinant protein
Western Blot (WB), ELISA (EIA)
Species
Human
Tag
N-terminal His-IF2DI Tag
Reconstitution
Centrifuge the vial at 10,000rpm for 1 minute, reconstitute at 200ug/ml in sterile distilled water
Preparation and Storage
Store at -20 degree C for 12 months as lyophilized; 2-8 degree C for 1 month under sterile conditions after reconstitution

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed MW 68kDa
Calculated MW 23kDa/68kDa
NCBI Official Full Name
Mitochondrial Rho GTPase 2
NCBI Official Synonym Full Names
ras homolog family member T2
NCBI Official Symbol
RHOT2
NCBI Official Synonym Symbols
RASL; ARHT2; MIRO2; MIRO-2; C16orf39
NCBI Protein Information
mitochondrial Rho GTPase 2; mitochondrial Rho (MIRO) GTPase 2; ras homolog gene family, member T2
UniProt Protein Name
Mitochondrial Rho GTPase 2
Protein Family
UniProt Gene Name
RHOT2
UniProt Synonym Gene Names
ARHT2; C16orf39; MIRO-2; hMiro-2
UniProt Entry Name
MIRO2_HUMAN

NCBI Description

This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011]

Uniprot Description

RHOT2: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Belongs to the mitochondrial Rho GTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; G protein, monomeric, Rho; Membrane protein, integral; G protein, monomeric; EC 3.6.5.-; Mitochondrial; G protein

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: membrane; plasma membrane; cytosol; integral to mitochondrial outer membrane

Molecular Function: GTPase activity; protein binding; GTP binding; calcium ion binding

Biological Process: regulation of small GTPase mediated signal transduction; metabolic process; small GTPase mediated signal transduction; cellular homeostasis; mitochondrion transport along microtubule

Research Articles on MIRO2

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Product Notes

The MIRO2 rhot2 (Catalog #AAA7614277) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 392-541. AAA Biotech's MIRO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the MIRO2 rhot2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIRO2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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