Rabbit ZFYVE16 Polyclonal Antibody | anti-ZFYVE16 antibody

ZFYVE16 Rabbit Polyclonal

Cat. Num. AAA7605861

• Gene Names: ZFYVE16; PPP1R69
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ZFYVE16; Polyclonal Antibody; ZFYVE16 Rabbit Polyclonal; anti-ZFYVE16 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 809

• Applicable Applications for anti-ZFYVE16 antibody: ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
• Immunogen: Zinc finger, FYVE domain containing 16
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS7605861 (ZFYVE16 antibody) at dilution of 1:200)

Western Blot (WB)

(MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with MBS7605861 (ZFYVE16 antibody) at dilution of 1:400)

NCBI and Uniprot Product Information

• NCBI GI #: 21411215
• NCBI GeneID: 9765
• Molecular Weight: 88,377 Da
• NCBI Official Full Name: ZFYVE16 protein
• NCBI Official Synonym Full Names: zinc finger FYVE-type containing 16
• NCBI Official Symbol: ZFYVE16
• NCBI Official Synonym Symbols: PPP1R69
• NCBI Protein Information: zinc finger FYVE domain-containing protein 16
• UniProt Protein Name: Zinc finger FYVE domain-containing protein 16
• Protein Family: Zinc finger FYVE domain-containing protein
• UniProt Gene Name: ZFYVE16
• UniProt Synonym Gene Names: KIAA0305
• UniProt Entry Name: ZFY16_HUMAN

NCBI Description

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

endofin: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q14

Cellular Component: cytoplasm; early endosome; early endosome membrane; intracellular membrane-bound organelle

Molecular Function: metal ion binding; phosphatidylinositol binding; phosphatidylinositol-3,4,5-triphosphate binding; protein binding; protein transporter activity

Biological Process: BMP signaling pathway; endosome transport; protein targeting to lysosome; regulation of endocytosis; signal transduction; vesicle organization and biogenesis