Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach using MBS7601426 (MIP antibody) at dilution of 1:100)
Rabbit MIP Polyclonal Antibody | anti-MIP antibody
MIP Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach using MBS7601426 (MIP antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach using MBS7601426 (MIP antibody) at dilution of 1:100)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7601426 (MIP antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7601426 (MIP antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008]
Uniprot Description
AQP0: major intrinsic protein of lens fiber. A member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. May be responsible for regulating the osmolarity of the lens. Defects in MIP are a cause of autosomal recessive congenital cataract.
Protein type: Transporter, aquaporin family; Membrane protein, multi-pass; Channel, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: apical plasma membrane; endoplasmic reticulum; gap junction; integral to plasma membrane; intracellular canaliculus; plasma membrane
Molecular Function: calmodulin binding; gap junction channel activity; glycerol channel activity; structural constituent of eye lens; transporter activity; water channel activity
Biological Process: canalicular bile acid transport; cellular water homeostasis; glycerol transport; lens development in camera-type eye; positive regulation of cell adhesion; protein homotetramerization; response to stimulus; visual perception; water transport
Disease: Cataract 15, Multiple Types
Research Articles on MIP
Similar Products
Product Notes
The MIP mip (Catalog #AAA7601426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MIP Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MIP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the MIP mip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
