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Immunohistochemistry (IHC) (Immunohistochemical of paraffin-embedded human kidney using MBS7601248 (MARK4 antibody) at dilution of 1:50)

Rabbit MARK4 Polyclonal Antibody | anti-MARK4 antibody

MARK4 Rabbit Polyclonal

Gene Names
MARK4; MARK4L; MARK4S; MARKL1; PAR-1D; MARKL1L
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
MARK4; Polyclonal Antibody; MARK4 Rabbit Polyclonal; anti-MARK4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
752
Applicable Applications for anti-MARK4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
MAP/microtubule affinity-regulating kinase 4
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemical of paraffin-embedded human kidney using MBS7601248 (MARK4 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemical of paraffin-embedded human kidney using MBS7601248 (MARK4 antibody) at dilution of 1:50)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,321 Da
NCBI Official Full Name
MAP/microtubule affinity-regulating kinase 4 isoform 1
NCBI Official Synonym Full Names
microtubule affinity regulating kinase 4
NCBI Official Symbol
MARK4
NCBI Official Synonym Symbols
MARK4L; MARK4S; MARKL1; PAR-1D; MARKL1L
NCBI Protein Information
MAP/microtubule affinity-regulating kinase 4
UniProt Protein Name
MAP/microtubule affinity-regulating kinase 4
UniProt Gene Name
MARK4
UniProt Synonym Gene Names
KIAA1860; MARKL1
UniProt Entry Name
MARK4_HUMAN

NCBI Description

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

MARK4: a member of the CAMKL family of protein kinases. Normally expressed in neural progenitors and is re-expressed in gliomas.

Protein type: CAMK group; CAMKL family; EC 2.7.11.1; Kinase, protein; MARK subfamily; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: centrosome; cytosol; microtubule cytoskeleton; microtubule organizing center; neuron projection

Molecular Function: gamma-tubulin binding; microtubule binding; protein binding; protein serine/threonine kinase activity; tau-protein kinase activity

Biological Process: microtubule bundle formation; microtubule cytoskeleton organization and biogenesis; nervous system development; protein amino acid phosphorylation

Research Articles on MARK4

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Product Notes

The MARK4 mark4 (Catalog #AAA7601248) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MARK4 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MARK4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MARK4 mark4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MARK4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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