Guinea Pig UbiA prenyltransferase domain-containing protein 1 (UBIAD1) ELISA Kit | UBIAD1 elisa kit
Guinea pig UbiA prenyltransferase domain-containing protein 1 (UBIAD1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein thought to be involved in cholesterol and phospholipid metabolism. Mutations in this gene are associated with Schnyder crystalline corneal dystrophy. [provided by RefSeq, Oct 2008]
Uniprot Description
UBIAD1: Prenyltransferase that mediates the formation of menaquinone-4 (MK-4), a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas. Mediates the conversion of phylloquinone (PK) into menaquinone-4 (MK-4), probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Defects in UBIAD1 are the cause of crystalline corneal dystrophy of Schnyder (SCCD). SCCD is a rare autosomal dominant disease characterized by progressive corneal opacification resulting from abnormal deposition of cholesterol and phospholipids. Belongs to the UbiA prenyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; EC 2.5.1.-; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p36.22
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; mitochondrial membrane; integral to Golgi membrane; nucleus
Molecular Function: antioxidant activity; protein binding; prenyltransferase activity
Biological Process: menaquinone biosynthetic process; ubiquinone biosynthetic process; vitamin K biosynthetic process
Disease: Schnyder Corneal Dystrophy
Research Articles on UBIAD1
Similar Products
Product Notes
The Guinea Pig UBIAD1 ubiad1 (Catalog #AAA7252090) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7252090 ELISA Kit recognizes Guinea Pig UBIAD1. It is sometimes possible for the material contained within the vial of "UbiA prenyltransferase domain-containing protein 1 (UBIAD1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
