Sheep CTD small phosphatase-like protein (CTDSPL) ELISA Kit | CTDSPL elisa kit

Sheep CTD small phosphatase-like protein (CTDSPL) ELISA Kit

Cat. Num. AAA7248724

• Gene Names: CTDSPL; PSR1; SCP3; HYA22; RBSP3; C3orf8
• Reactivity: Sheep
• Synonyms: CTD small phosphatase-like protein (CTDSPL); Sheep CTD small phosphatase-like protein (CTDSPL) ELISA Kit; CTDSPL elisa kit

• Reactivity: Sheep

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Preparation and Storage: Store all reagents at 2-8 degree C.

Product Categories/Family for CTDSPL elisa kit

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 56549681
• NCBI GeneID: 10217
• NCBI Accession #: NP_005799.2
• NCBI GenBank Nucleotide #: NM_005808.2
• Molecular Weight: 29,937 Da
• NCBI Official Full Name: CTD small phosphatase-like protein isoform 2
• NCBI Official Synonym Full Names: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
• NCBI Official Symbol: CTDSPL
• NCBI Official Synonym Symbols: PSR1; SCP3; HYA22; RBSP3; C3orf8
• NCBI Protein Information: CTD small phosphatase-like protein; CTDSP-like; NIF-like protein; small CTD phosphatase 3; NLI-interacting factor 1; small C-terminal domain phosphatase 3; nuclear LIM interactor-interacting factor 1; RB protein serine phosphatase from chromosome 3; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3
• UniProt Protein Name: CTD small phosphatase-like protein
• Protein Family: CTD small phosphatase-like protein
• UniProt Gene Name: CTDSPL
• UniProt Synonym Gene Names: C3orf8; NIF1; NIFL; SCP3; YA22; CTDSP-like; NLI-interacting factor 1; hYA22; SCP3; Small CTD phosphatase 3
• UniProt Entry Name: CTDSL_HUMAN

Uniprot Description

CTDSPL: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphatase; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: nucleus

Molecular Function: metal ion binding; phosphoprotein phosphatase activity

Biological Process: dephosphorylation; negative regulation of protein amino acid phosphorylation