Typical Testing Data/Standard Curve (for reference only)
Human Transcription factor SOX 11 (SOX11) ELISA Kit | SOX11 elisa kit
Human Transcription factor SOX 11 (SOX11) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: SOX11 ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-SOX11 antibody and an SOX11-HRP conjugate. The assay sample and buffer are incubated together with SOX11-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the SOX11 concentration since SOX11 from samples and SOX11-HRP conjugate compete for the anti-SOX11 antibody binding site. Since the number of sites is limited, as more sites are occupied by SOX11 from the sample, fewer sites are left to bind SOX11-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The SOX11 concentration in each sample is interpolated from this standard curve.
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; nucleus
Molecular Function: translation factor activity, nucleic acid binding; transcription factor activity
Biological Process: neural crest cell development; translation; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of lymphocyte proliferation; glial cell proliferation; neuron differentiation; sympathetic nervous system development; regulation of transforming growth factor beta receptor signaling pathway; embryonic digestive tract morphogenesis; positive regulation of cell proliferation; hard palate development; kidney development; oligodendrocyte development; skeletal development; positive regulation of BMP signaling pathway; glial cell development; positive regulation of neurogenesis; transcription, DNA-dependent; positive regulation of hormone secretion; positive regulation of ossification; embryonic skeletal morphogenesis; limb bud formation; positive regulation of osteoblast differentiation; spinal cord development; lens morphogenesis in camera-type eye; positive regulation of transcription from RNA polymerase II promoter; soft palate development; neural tube formation; positive regulation of neuron differentiation
Disease: Mental Retardation, Autosomal Dominant 27
Research Articles on SOX11
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Product Notes
The Human SOX11 sox11 (Catalog #AAA7245737) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7245737 ELISA Kit recognizes Human SOX11. It is sometimes possible for the material contained within the vial of "Transcription factor SOX 11 (SOX11), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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