Guinea Pig Active breakpoint cluster region-related protein (ABR) ELISA Kit | ABR elisa kit
Guinea pig Active breakpoint cluster region-related protein (ABR) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
ABR: GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; Kinase, protein; GAPs; Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; BCR family
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: membrane; plasma membrane; cytosol
Molecular Function: Rho guanyl-nucleotide exchange factor activity; GTPase activator activity
Biological Process: inner ear morphogenesis; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; response to lipopolysaccharide; regulation of small GTPase mediated signal transduction; negative regulation of neutrophil degranulation; negative regulation of inflammatory response; positive regulation of phagocytosis; small GTPase mediated signal transduction; brain development; actin cytoskeleton organization and biogenesis; neuromuscular process controlling balance; negative regulation of cell migration
Disease: Medulloblastoma
Research Articles on ABR
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Product Notes
The Guinea Pig ABR abr (Catalog #AAA7244717) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7244717 ELISA Kit recognizes Guinea Pig ABR. It is sometimes possible for the material contained within the vial of "Active breakpoint cluster region-related protein (ABR), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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