NCBI Description
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
Uniprot Description
TNNC2: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q12-q13.11
Cellular Component: troponin complex; cytosol
Molecular Function: calcium ion binding; actin binding
Biological Process: skeletal muscle contraction; regulation of muscle contraction; muscle filament sliding
Product Notes
The Human TNNC2 tnnc2 (Catalog #
AAA723828) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA723828 ELISA Kit recognizes Human TNNC2.
It is sometimes possible for the material contained within the vial of
"Troponin C Type 2, Fast, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
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