Rat Apoptosis-stimulating of p53 protein 2 (TP53BP2) ELISA Kit | TP53BP2 elisa kit
Rat Apoptosis-stimulating of p53 protein 2 (TP53BP2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
53BP2: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. Belongs to the ASPP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus
Molecular Function: NF-kappaB binding; identical protein binding; SH3 domain binding
Biological Process: embryonic development ending in birth or egg hatching; central nervous system development; apoptosis; heart development; response to ionizing radiation; cell cycle
Research Articles on TP53BP2
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Product Notes
The Rat TP53BP2 tp53bp2 (Catalog #AAA7236033) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7236033 ELISA Kit recognizes Rat TP53BP2. It is sometimes possible for the material contained within the vial of "Apoptosis-stimulating of p53 protein 2 (TP53BP2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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