Typical Testing Data/Standard Curve (for reference only)
Human C X C chemokine receptor type 6 (CXCR6) ELISA Kit | CXCR6 elisa kit
Human C X C chemokine receptor type 6 (CXCR6) ELISA Kit
Gene Names
CXCR6; BONZO; CD186; STRL33; TYMSTR
Reactivity
Human
Synonyms
C X C chemokine receptor type 6 (CXCR6); Human C X C chemokine receptor type 6 (CXCR6) ELISA Kit; CXCR6 elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of CXCR6. No significant cross-reactivity or interference between CXCR6 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between CXCR6 and all the analogues, therefore, cross reaction may still exist in some cases.
Samples
Serum, plasma, cell culture supernatants, body fluid and tissue homogenate
Assay Type
Quantitative Competitive
Sensitivity
0.1 ng/mL
Preparation and Storage
Store all reagents at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for CXCR6 elisa kit
Intended Uses: This CXCR6 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of HumanCXCR6. This ELISA kit for research use only, not for therapeutic or test applications!
Principle of the Assay: CXCR6 ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-CXCR6 antibody and an CXCR6-HRP conjugate. The assay sample and buffer are incubated together with CXCR6-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the CXCR6 concentration since CXCR6 from samples and CXCR6-HRP conjugate compete for the anti-CXCR6 antibody binding site. Since the number of sites is limited, as more sites are occupied by CXCR6 from the sample, fewer sites are left to bind CXCR6-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CXCR6 concentration in each sample is interpolated from this standard curve.
Principle of the Assay: CXCR6 ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-CXCR6 antibody and an CXCR6-HRP conjugate. The assay sample and buffer are incubated together with CXCR6-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the CXCR6 concentration since CXCR6 from samples and CXCR6-HRP conjugate compete for the anti-CXCR6 antibody binding site. Since the number of sites is limited, as more sites are occupied by CXCR6 from the sample, fewer sites are left to bind CXCR6-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CXCR6 concentration in each sample is interpolated from this standard curve.
Product Categories/Family for CXCR6 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,280 Da
NCBI Official Full Name
C-X-C chemokine receptor type 6
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 6
NCBI Official Symbol
CXCR6
NCBI Official Synonym Symbols
BONZO; CD186; STRL33; TYMSTR
NCBI Protein Information
C-X-C chemokine receptor type 6; CDw186; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33
UniProt Protein Name
C-X-C chemokine receptor type 6
Protein Family
UniProt Gene Name
CXCR6
UniProt Synonym Gene Names
BONZO; STRL33; TYMSTR; CXC-R6; CXCR-6
UniProt Entry Name
CXCR6_HUMAN
Uniprot Description
CXCR6: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3p21
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; coreceptor activity; C-X-C chemokine receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; viral genome replication; chemotaxis; inflammatory response
Research Articles on CXCR6
Similar Products
Product Notes
The Human CXCR6 cxcr6 (Catalog #AAA7232285) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7232285 ELISA Kit recognizes Human CXCR6. It is sometimes possible for the material contained within the vial of "C X C chemokine receptor type 6 (CXCR6), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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