Human RNA binding protein with multiple splicing (RBPMS) ELISA Kit | RBPMS elisa kit
Human RNA binding protein with multiple splicing (RBPMS) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Uniprot Description
RBPMS: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p12
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: protein binding; transcription coactivator activity; nucleotide binding; poly(A) binding
Biological Process: RNA processing; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on RBPMS
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Product Notes
The Human RBPMS rbpms (Catalog #AAA7230269) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7230269 ELISA Kit recognizes Human RBPMS. It is sometimes possible for the material contained within the vial of "RNA binding protein with multiple splicing (RBPMS), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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