Mouse Zinc finger and BTB domain-containing protein 17 (ZBTB17) ELISA Kit | ZBTB17 elisa kit
Mouse Zinc finger and BTB domain-containing protein 17 (ZBTB17) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008]
Uniprot Description
ZBTB17: May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation. Belongs to the krueppel C2H2-type zinc-finger protein family. Binds to the C-terminal helix-loop-helix motif of MYC which inhibits ZBTB17 transactivation and growth arrest activities and renders it insoluble in the nucleus. Also interacts with HCFC1, MAGEA4 and TMPRSS11A. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 1p36.13
Cellular Component: nucleoplasm
Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor activity
Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; transcription, DNA-dependent; unfolded protein response; positive regulation of transcription, DNA-dependent; ectoderm development; gastrulation with mouth forming second; negative regulation of cell cycle
Research Articles on ZBTB17
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Product Notes
The Mouse ZBTB17 zbtb17 (Catalog #AAA7224322) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7224322 ELISA Kit recognizes Mouse ZBTB17. It is sometimes possible for the material contained within the vial of "Zinc finger and BTB domain-containing protein 17 (ZBTB17), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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