Sheep Chromatin modification-related protein MEAF6 (C1orf149) ELISA Kit | C1orf149 elisa kit
Sheep Chromatin modification-related protein MEAF6 (C1orf149) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nuclear protein involved in transcriptional activation. The encoded protein may form a component of several different histone acetyltransferase complexes. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
MEAF6: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Belongs to the EAF6 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function; Nucleolus
Chromosomal Location of Human Ortholog: 1p35.3-p33
Cellular Component: nucleoplasm; centrosome; NuA4 histone acetyltransferase complex; cytoplasm; nucleolus
Molecular Function: protein binding
Biological Process: establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on C1orf149
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Product Notes
The Sheep C1orf149 meaf6 (Catalog #AAA7218791) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7218791 ELISA Kit recognizes Sheep C1orf149. It is sometimes possible for the material contained within the vial of "Chromatin modification-related protein MEAF6 (C1orf149), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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