Bovine Centromere protein U (MLF1IP) ELISA Kit | CENPU elisa kit

Bovine Centromere protein U (MLF1IP) ELISA Kit

Gene Names

CENPU; KLIP1; PBIP1; CENP50; MLF1IP; CENPU50

Reactivity

Bovine

Synonyms

Centromere protein U (MLF1IP); Bovine Centromere protein U (MLF1IP) ELISA Kit; CENPU elisa kit

Ordering
Cat. Num. AAA7214225 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Bovine

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Preparation and Storage

Store all reagents at 2-8 degree C.

Product Categories/Family for CENPU elisa kit

Cell Biology

NCBI and Uniprot Product Information

NCBI GI #

38016935

NCBI GeneID

79682

NCBI Accession #

NP_078905.2

NCBI GenBank Nucleotide #

NM_024629.3

Molecular Weight

38,102 Da

NCBI Official Full Name

centromere protein U

NCBI Official Synonym Full Names

centromere protein U

NCBI Official Symbol

CENPU

NCBI Official Synonym Symbols

KLIP1; PBIP1; CENP50; MLF1IP; CENPU50

NCBI Protein Information

centromere protein U; MLF1 interacting protein; MLF1-interacting protein; centromere protein of 50 kDa; polo-box-interacting protein 1; interphase centromere complex protein 24; KSHV latent nuclear antigen interacting protein 1; KSHV latent nuclear antigen-interacting protein 1

UniProt Protein Name

Centromere protein U

Protein Family

Centromere protein

UniProt Gene Name

CENPU

UniProt Synonym Gene Names

ICEN24; KLIP1; MLF1IP; PBIP1; CENP-U; CENP-50

UniProt Entry Name

CENPU_HUMAN

NCBI Description

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

Uniprot Description

CENPU: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: nucleoplasm; microtubule organizing center; cytosol; nucleus

Biological Process: nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; chordate embryonic development; viral reproduction; regulation of transcription, DNA-dependent; transcription, DNA-dependent; mitotic cell cycle

Research Articles on CENPU

1. Data propose that CENP-P/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.

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Product Notes

The Bovine CENPU cenpu (Catalog #AAA7214225) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7214225 ELISA Kit recognizes Bovine CENPU. It is sometimes possible for the material contained within the vial of "Centromere protein U (MLF1IP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Bovine Centromere protein U (MLF1IP) ELISA Kit | CENPU elisa kit