Goat Estradiol 17-beta-dehydrogenase 8 (HSD17B8) ELISA Kit | HSD17B8 elisa kit
Goat Estradiol 17-beta-dehydrogenase 8 (HSD17B8) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
HSD17B8: NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein type: EC 1.1.1.62; Lipid Metabolism - androgen and estrogen; Oxidoreductase; Mitochondrial; EC 1.1.1.239
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: mitochondrial envelope; mitochondrial matrix; plasma membrane
Molecular Function: estradiol 17-beta-dehydrogenase activity; protein binding; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity; 3-hydroxyacyl-CoA dehydrogenase activity
Biological Process: androgen metabolic process; estrogen biosynthetic process; fatty acid biosynthetic process
Research Articles on HSD17B8
Similar Products
Product Notes
The Goat HSD17B8 hsd17b8 (Catalog #AAA7213845) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7213845 ELISA Kit recognizes Goat HSD17B8. It is sometimes possible for the material contained within the vial of "Estradiol 17-beta-dehydrogenase 8 (HSD17B8), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
