Monkey Codanin-1 (CDAN1) ELISA Kit | CDAN1 elisa kit
Monkey Codanin-1 (CDAN1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that appears to play a role in nuclear envelope integrity, possibly related to microtubule attachments. Mutations in this gene cause congenital dyserythropoietic anemia type I, a disease resulting in morphological and functional abnormalities of erythropoiesis. [provided by RefSeq, Jul 2009]
Uniprot Description
CDAN1: Might be involved in nuclear membrane integrity. Defects in CDAN1 are the cause of congenital dyserythropoietic anemia type 1 (CDA1). An autosomal recessive blood disorder characterized by morphological abnormalities of erythroblasts, ineffective erythropoiesis, macrocytic anemia and secondary hemochromatosis. It is occasionally associated with bone abnormalities, especially of the hands and feet (acrodysostosis), nail hypoplasia, and scoliosis. Ultrastructural features include internuclear chromatin bridges connecting some nearly completely separated erythroblasts and an abnormal appearance (spongy or Swiss-cheese appearance) of the heterochromatin in a high proportion of the erythroblasts. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q15.2
Cellular Component: cytoplasm; plasma membrane; integral to membrane; endomembrane system; nucleus
Molecular Function: protein binding
Biological Process: protein localization; establishment and/or maintenance of chromatin architecture; negative regulation of DNA replication; chromatin assembly
Disease: Anemia, Congenital Dyserythropoietic, Type Ia
Research Articles on CDAN1
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Product Notes
The Monkey CDAN1 cdan1 (Catalog #AAA7208523) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7208523 ELISA Kit recognizes Monkey CDAN1. It is sometimes possible for the material contained within the vial of "Codanin-1 (CDAN1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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