Guinea Pig Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) ELISA Kit | CTDSP2 elisa kit
Guinea pig Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CTDSP2: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.
Protein type: Phosphatase; Nuclear receptor co-regulator; EC 3.1.3.16
Chromosomal Location of Human Ortholog: 12q14.1
Cellular Component: nucleoplasm
Molecular Function: protein binding; metal ion binding; CTD phosphatase activity
Biological Process: cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; negative regulation of protein amino acid phosphorylation; unfolded protein response; protein amino acid dephosphorylation
Research Articles on CTDSP2
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Product Notes
The Guinea Pig CTDSP2 ctdsp2 (Catalog #AAA7202030) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7202030 ELISA Kit recognizes Guinea Pig CTDSP2. It is sometimes possible for the material contained within the vial of "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (CTDSP2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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