Rabbit SLU7 splicing factor homolog Polyclonal Antibody | anti-SLU7 antibody
Rabbit anti-human SLU7 splicing factor homolog (S. cerevisiae) polyclonal Antibody
NCBI and Uniprot Product Information
NCBI Description
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008]
Uniprot Description
SLU7: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family.
Protein type: RNA splicing; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 5q33.3
Cellular Component: nucleoplasm; small nuclear ribonucleoprotein complex; spliceosome; membrane; intracellular membrane-bound organelle; cytoplasm; nuclear speck; nucleus
Molecular Function: protein binding; zinc ion binding; second spliceosomal transesterification activity; pre-mRNA 3'-splice site binding
Biological Process: nuclear mRNA splicing, via spliceosome; nuclear mRNA 3'-splice site recognition; alternative nuclear mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; intracellular protein transport
Research Articles on SLU7
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Product Notes
The SLU7 slu7 (Catalog #AAA719150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human SLU7 splicing factor homolog (S. cerevisiae) polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLU7 splicing factor homolog can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SLU7 slu7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLU7 splicing factor homolog, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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