Rabbit LASV Polyclonal Antibody | anti-LASV antibody

Rabbit anti-Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)(LASV) Z Polyclonal Antibody

• Reactivity: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)(LASV)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: LASV; Polyclonal Antibody; Rabbit anti-Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)(LASV) Z Polyclonal Antibody; Z Antibody; RING finger protein Z; Protein Z; Zinc-binding protein); Z; anti-LASV antibody

• Host: Rabbit
• Reactivity: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)(LASV)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-LASV antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Lassa virus RING finger protein Z (Z)
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 23343513
• NCBI GeneID: 956586
• NCBI Accession #: NP_694871.1
• NCBI GenBank Nucleotide #: NC_004297.1
• UniProt Accession #: O73557
• Molecular Weight: 10,675 Da
• NCBI Official Full Name: Z protein
• NCBI Official Symbol: LASVsLgp1
• NCBI Protein Information: Z protein
• UniProt Protein Name: RING finger protein Z
• UniProt Gene Name: Z
• UniProt Synonym Gene Names: Protein Z

Uniprot Description

Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (). Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E.