Ras-related protein Rab-25 (RAB25) Recombinant Protein | RAB25 recombinant protein

Recombinant Human Ras-related protein Rab-25 (RAB25)

Cat. Num. AAA717994

• Gene Names: RAB25; CATX-8; RAB11C
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ras-related protein Rab-25 (RAB25); Recombinant Human Ras-related protein Rab-25 (RAB25); RAB25 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-210, Full length protein
• Sequence: MGNGTEEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNSIRTNAITLGSAQAGQEPGPGEKRACC
• Sequence Length: 210

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 116812567
• NCBI GeneID: 57111
• NCBI Accession #: NP_065120.2
• NCBI GenBank Nucleotide #: NM_020387.3
• UniProt Accession #: P57735; Q5VYA2; Q8NG24; Q96GB1; Q9BT12
• Molecular Weight: 23,496 Da
• NCBI Official Full Name: ras-related protein Rab-25
• NCBI Official Synonym Full Names: RAB25, member RAS oncogene family
• NCBI Official Symbol: RAB25
• NCBI Official Synonym Symbols: CATX-8; RAB11C
• NCBI Protein Information: ras-related protein Rab-25
• UniProt Protein Name: Ras-related protein Rab-25
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB25

NCBI Description

The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded protein is involved in membrane trafficking and cell survival. This gene has been found to be a tumor suppressor and an oncogene, depending on the context. Two variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2015]

Uniprot Description

Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis ().