Rabbit TAT Polyclonal Antibody | anti-TAT antibody

Rabbit anti-Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2) TAT Polyclonal Antibody

Reactivity

Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2)

Applications

ELISA, Western Blot

Purity

Protein A/G

Synonyms

TAT; Polyclonal Antibody; Rabbit anti-Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2) TAT Polyclonal Antibody; TAT Antibody; Protein Tat; Transactivating regulatory protein; tat; anti-TAT antibody

Ordering

Host

Rabbit

Reactivity

Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2)

Clonality

Polyclonal

Isotype

IgG

Purity/Purification

Protein A/G

Form/Format

Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4

Applicable Applications for anti-TAT antibody

ELISA (EIA), WB (Western Blot) (ensure identification of antigen)

Immunogen

Recombinant Human immunodeficiency virus type 2 subtype A (isolate Ghana-1) (HIV-2) tat protein

Conjugation

Non-conjugate

Modification

Unmodified

Deliverables

1. 200ug recombinant immunogen protein/peptide (positive control).
2. 1mL preimmune serum (negative control)
3. 10mg rabbit polyclonal antibody purified by Protein A/G.

Quality Guarantee

1. Antibody purity >90% confirmed by SDS-PAGE.
2. Antibody titer > 1: 64,000 confirmed by ELISA
3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).

Complementary Antibody

Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:
* 6*His Monoclonal Antibody #MBS1491670
* DYKDDDDK tag Monoclonal Antibody #MBS1493946
* GAPDH Monoclonal Antibody #MBS1495524
* GFP Monoclonal Antibody #MBS1496050
* Myc tag Monoclonal Antibody #MBS1497694
* GST Monoclonal Antibody #MBS1497871
* Sumo tag Monoclonal Antibody #MBS1498878
* Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510
* HA-Tag Monoclonal Antibody #MBS7135631
* E-Tag Monoclonal Antibody #MBS7135632
* TUBA1A Monoclonal Antibody #MBS7135645
* TUBB Monoclonal Antibody #MBS9018332

Preparation and Storage

Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

NCBI GI #

135360

UniProt Accession #

P18044

Molecular Weight

11,225 Da

NCBI Official Full Name

Protein Tat

UniProt Protein Name

Protein Tat

Protein Family

Tat-binding

UniProt Gene Name

tat

Uniprot Description

Nuclear transcriptional activator of viral gene expression, that is essential for viral transcription from the LTR promoter and replication. Acts as a sequence-specific molecular adapter, directing components of the cellular transcription machinery to the viral RNA to promote processive transcription elongation by the RNA polymerase II (RNA pol II) complex, thereby increasing the level of full-length transcripts. In the absence of Tat, the RNA Pol II generates short or non-processive transcripts that terminate at approximately 60 bp from the initiation site. Tat associates with the CCNT1/cyclin-T1 component of the P-TEFb complex (CDK9 and CCNT1), which promotes RNA chain elongation. This binding increases Tat's affinity for a hairpin structure at the 5'-end of all nascent viral mRNAs referred to as the transactivation responsive RNA element (TAR RNA) and allows Tat/P-TEFb complex to bind cooperatively to TAR RNA. The CDK9 component of P-TEFb and other Tat-activated kinases hyperphosphorylate the C-terminus of RNA Pol II that becomes stabilized and much more processive ().

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Product Notes

The TAT tat (Catalog #AAA7152908) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2) TAT Polyclonal Antibody reacts with Human immunodeficiency virus type 2 subtype A (isolate Ghana-1)(HIV-2) and may cross-react with other species as described in the data sheet. AAA Biotech's TAT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), WB (Western Blot) (ensure identification of antigen). Researchers should empirically determine the suitability of the TAT tat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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