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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7125790(HYAL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit anti-Human, Rat HYAL3 Polyclonal Antibody | anti-HYAL3 antibody

HYAL3 Antibody

Gene Names
HYAL3; LUCA3; HYAL-3; LUCA-3
Reactivity
Human, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
HYAL3; Polyclonal Antibody; HYAL3 Antibody; hyaluronoglucosaminidase 3; anti-HYAL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-HYAL3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Fusion protein of human HYAL3
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7125790(HYAL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7125790(HYAL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using MBS7125790(HYAL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using MBS7125790(HYAL3 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200))

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human kidney tissue, Primary antibody: MBS7125790(HYAL3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)

SDS-Page (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human kidney tissue, Primary antibody: MBS7125790(HYAL3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)
Product Categories/Family for anti-HYAL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,501 Da
NCBI Official Full Name
hyaluronidase
NCBI Official Synonym Full Names
hyaluronoglucosaminidase 3
NCBI Official Symbol
HYAL3
NCBI Official Synonym Symbols
LUCA3; HYAL-3; LUCA-3
NCBI Protein Information
hyaluronidase-3; lung carcinoma protein 3
UniProt Protein Name
Hyaluronidase-3
UniProt Gene Name
HYAL3
UniProt Synonym Gene Names
LUCA3; Hyal-3; LuCa-3
UniProt Entry Name
HYAL3_HUMAN

NCBI Description

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Uniprot Description

HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Protein type: Hydrolase; EC 3.2.1.35; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: lysosome; extracellular region; cytoplasmic vesicle

Molecular Function: viral receptor activity; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity

Biological Process: response to antibiotic; cartilage development; response to virus; carbohydrate metabolic process; inflammatory response; hyaluronan catabolic process

Research Articles on HYAL3

Similar Products

Product Notes

The HYAL3 hyal3 (Catalog #AAA7125790) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HYAL3 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HYAL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the HYAL3 hyal3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HYAL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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