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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using MBS7123272(ABCB5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit anti-Human, Mouse ABCB5 Polyclonal Antibody | anti-ABCB5 antibody

ABCB5 Antibody

Gene Names
ABCB5; ABCB5beta; EST422562; ABCB5alpha
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ABCB5; Polyclonal Antibody; ABCB5 Antibody; ATP-binding cassette sub-family B member 5; anti-ABCB5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-ABCB5 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:500-1:2000
IHC: 1:10-1:50
Immunogen
Fusion protein of human ABCB5
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using MBS7123272(ABCB5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using MBS7123272(ABCB5 Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200))
Product Categories/Family for anti-ABCB5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
89,832 Da
NCBI Official Full Name
ATP-binding cassette sub-family B member 5 isoform 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family B (MDR/TAP), member 5
NCBI Official Symbol
ABCB5
NCBI Official Synonym Symbols
ABCB5beta; EST422562; ABCB5alpha
NCBI Protein Information
ATP-binding cassette sub-family B member 5; ABCB5 P-gp; ATP-binding cassette protein; P-glycoprotein ABCB5
UniProt Protein Name
ATP-binding cassette sub-family B member 5
Protein Family
UniProt Gene Name
ABCB5
UniProt Entry Name
ABCB5_HUMAN

NCBI Description

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]

Uniprot Description

ABCB5: Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas. Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: efflux transmembrane transporter activity; ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: regulation of membrane potential; metabolic process; compound eye corneal lens development; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; cell differentiation; antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; transmembrane transport; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

Research Articles on ABCB5

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Product Notes

The ABCB5 abcb5 (Catalog #AAA7123272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCB5 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ABCB5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:500-1:2000 IHC: 1:10-1:50. Researchers should empirically determine the suitability of the ABCB5 abcb5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCB5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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