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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200)

Rabbit ADI1 Polyclonal Antibody | anti-ADI1 antibody

ADI1 Antibody

Gene Names
ADI1; ARD; APL1; SIPL; mtnD; Fe-ARD; MTCBP1; Ni-ARD; HMFT1638
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synonyms
ADI1; Polyclonal Antibody; ADI1 Antibody; 1;2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) (Submergence-induced protein-like factor) (Sip-L); anti-ADI1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, Containing 0.02% Sodium Azide as Preservative and 50% Glycerol.
Applicable Applications for anti-ADI1 antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes
IHC-P: 1:50-300
ELISA: 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 71-120
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200)
Product Categories/Family for anti-ADI1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
179
NCBI Official Full Name
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
NCBI Official Synonym Full Names
acireductone dioxygenase 1
NCBI Official Symbol
ADI1
NCBI Official Synonym Symbols
ARD; APL1; SIPL; mtnD; Fe-ARD; MTCBP1; Ni-ARD; HMFT1638
NCBI Protein Information
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; ARD; ADI1; fe-ARD; MTCBP-1; submergence induced protein 2; submergence-induced protein-like factor; MT1-MMP cytoplasmic tail-binding protein-1; acireductone dioxygenase (Fe(2+)-requiring); acireductone
UniProt Protein Name
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
UniProt Gene Name
ADI1
UniProt Entry Name
MTND_HUMAN

NCBI Description

This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. [provided by RefSeq, May 2010]

Uniprot Description

ADI1: Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. Belongs to the acireductone dioxygenase (ARD) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 1.13.11.54; Oxidoreductase

Chromosomal Location of Human Ortholog: 2p25.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus; cytosol

Molecular Function: acireductone dioxygenase [iron(II)-requiring] activity; protein binding; iron ion binding; oxidoreductase activity

Biological Process: methionine salvage; sulfur amino acid metabolic process; polyamine metabolic process

Research Articles on ADI1

Similar Products

Product Notes

The ADI1 adi1 (Catalog #AAA7122930) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADI1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADI1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, ELISA (EIA). IHC-P: 1:50-300 ELISA: 1:10000-20000. Researchers should empirically determine the suitability of the ADI1 adi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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