Western Blot (WB)
(Western Blot analysis of Jurkat cells using SURF-1 Polyclonal Antibody)
Rabbit SURF1 Polyclonal Antibody | anti-SURF1 antibody
SURF1 Antibody
IHC: 1:100-1:300
IF: 1:200-1:1000
ELISA: 1:20000
Western Blot (WB)
(Western Blot analysis of Jurkat cells using SURF-1 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Jurkat cells using SURF-1 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Jurkat cells using SURF-1 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Jurkat cells using SURF-1 Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008]
Uniprot Description
SURF1: Probably involved in the biogenesis of the COX complex. Defects in SURF1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the SURF1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Oxidoreductase; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q34.2
Cellular Component: integral to membrane; mitochondrial respiratory chain
Molecular Function: protein binding; cytochrome-c oxidase activity
Biological Process: respiratory chain complex IV assembly; ATP biosynthetic process; aerobic respiration; oxidative phosphorylation
Disease: Leigh Syndrome
Research Articles on SURF1
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Product Notes
The SURF1 surf1 (Catalog #AAA7122358) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SURF1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SURF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:100-1:300 IF: 1:200-1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the SURF1 surf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SURF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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