Rabbit VPX Polyclonal Antibody | anti-VPX antibody
VPX Antibody, HRP Conjugated
Reactivity
Human Immunodeficiency Virus Type 2 Subtype A
Applications
ELISA
Purity
>95%Protein G Purified
Synonyms
VPX; Polyclonal Antibody; VPX Antibody; HRP Conjugated; Protein Vpx; Viral protein X; X ORF protein; vpx; anti-VPX antibody
Host
Rabbit
Reactivity
Human Immunodeficiency Virus Type 2 Subtype A
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%
Protein G Purified
Protein G Purified
Form/Format
Liquid
Sequence Length
112
Applicable Applications for anti-VPX antibody
ELISA (EIA)
Immunogen Species
Human Immunodeficiency Virus Type 2 Subtype A
Immunogen
Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-112AA)
Conjugate
HRP
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.
NCBI and Uniprot Product Information
Uniprot Description
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription ().
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Product Notes
The VPX vpx (Catalog #AAA7113803) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPX Antibody, HRP Conjugated reacts with Human Immunodeficiency Virus Type 2 Subtype An and may cross-react with other species as described in the data sheet. AAA Biotech's VPX can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the VPX vpx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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