Rabbit anti-Human NASP Polyclonal Antibody | anti-NASP antibody

NASP Antibody

Cat. Num. AAA7045956

• Gene Names: NASP; HMDRA1; FLB7527; PRO1999
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: NASP; Polyclonal Antibody; NASP Antibody; Nuclear autoantigenic sperm protein; anti-NASP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 724

• Applicable Applications for anti-NASP antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC: 1:20-1:200
• Species: Human
• Immunogen: Recombinant human Nuclear autoantigenic sperm protein (C-270AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161914 / sc-161915 / sc-161916
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7045956 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045956 at dilution 1:100)

Related Product Information for anti-NASP antibody

Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 304434531
• NCBI GeneID: 4678
• NCBI Accession #: NP_001182122.1
• NCBI GenBank Nucleotide #: NM_001195193.1
• UniProt Accession #: P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2; A8K6H2; B4DQP3; D3DQ07; F5H3J2
• Molecular Weight: 78,450 Da
• NCBI Official Full Name: nuclear autoantigenic sperm protein isoform 4
• NCBI Official Synonym Full Names: nuclear autoantigenic sperm protein
• NCBI Official Symbol: NASP
• NCBI Official Synonym Symbols: HMDRA1; FLB7527; PRO1999
• NCBI Protein Information: nuclear autoantigenic sperm protein
• UniProt Protein Name: Nuclear autoantigenic sperm protein
• Protein Family: NASP-related protein
• UniProt Gene Name: NASP
• UniProt Synonym Gene Names: NASP
• UniProt Entry Name: NASP_HUMAN

NCBI Description

This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008]

Uniprot Description

Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA ().