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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lymphoid tissue using MBS7044904 at dilution of 1:100)

Rabbit anti-Human MYO1G Polyclonal Antibody | anti-MYO1G antibody

MYO1G Antibody

Gene Names
MYO1G; HA2; MHAG; HLA-HA2
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
MYO1G; Polyclonal Antibody; MYO1G Antibody; Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2 (mHag HA-2)]; HA2; anti-MYO1G antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-MYO1G antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC:1:20-1:200
IF:1:50-1:200
Immunogen
Recombinant Human Unconventional myosin-Ig protein (209-389AA)
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Species
Human
Research Area
Signal Transduction
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lymphoid tissue using MBS7044904 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lymphoid tissue using MBS7044904 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human appendix tissue using MBS7044904 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human appendix tissue using MBS7044904 at dilution of 1:100)

Immunofluorescent (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7044904 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescent (IF) (Immunofluorescent analysis of HepG2 cells using MBS7044904 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-MYO1G antibody
Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
unconventional myosin-Ig
NCBI Official Synonym Full Names
myosin IG
NCBI Official Symbol
MYO1G
NCBI Official Synonym Symbols
HA2; MHAG; HLA-HA2
NCBI Protein Information
unconventional myosin-Ig
UniProt Protein Name
Unconventional myosin-Ig
Protein Family
UniProt Gene Name
MYO1G
UniProt Synonym Gene Names
HA2; mHag HA-2
UniProt Entry Name
MYO1G_HUMAN

NCBI Description

MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010]

Uniprot Description

MYO1G: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Contractile; Motor

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: membrane; phagocytic cup; plasma membrane

Molecular Function: phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding

Biological Process: T cell mediated immunity

Research Articles on MYO1G

Similar Products

Product Notes

The MYO1G myo1g (Catalog #AAA7044904) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYO1G Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYO1G can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC:1:20-1:200 IF:1:50-1:200. Researchers should empirically determine the suitability of the MYO1G myo1g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYO1G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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