Mitochondrial cardiolipin hydrolase Recombinant Protein | CHLREDRAFT_190403 recombinant protein
Mitochondrial cardiolipin hydrolase
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
Plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (). piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability. Backbone-non-specific, single strand-specific nuclease, cleaving either RNA or DNA substrates with similar affinity (). Produces 5' phosphate and 3' hydroxyl termini, suggesting it could directly participate in the processing of primary piRNA transcripts (). Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface. Although it cannot be excluded that it can act as a phospholipase in some circumstances, this activity could not be confirmed ().
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Product Notes
The CHLREDRAFT_190403 chlredraft_190403 (Catalog #AAA7043201) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-223aa; full length protein. The amino acid sequence is listed below: MGCASSKEEV ALTPLSDVNA AKEVADLKAQ VDQLKRQLAS AGQSAAPAAA GAVKGGVVET LFFPDEKLPC RNNRRPGGCK RQHCEYSHTP TSLSRFLDYL GSATRTLDIC VFTITNDDIS DVVLELHNKG VRVRIISDND QAHTQGSDID KFRQAGIAVR QDKTAAHMHH KFAIIDGRLL LNGSFNWTRQ AVTANNENVT VLSDPKLIAS FQQQFDKLWD MFK. It is sometimes possible for the material contained within the vial of "Mitochondrial cardiolipin hydrolase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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