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Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) Recombinant Protein | TIMM22 recombinant protein

Recombinant Human Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22)

Gene Names
TIMM22; TEX4; TIM22
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22); Recombinant Human Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22); TIMM22 recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
1-194aa; full length protein
Sequence
MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQK MIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQ RGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCG GFAAFSAAIDYYLR
Sequence Length
Full length protein
Application Notes
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Species
Human
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Product Categories/Family for TIMM22 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,031 Da
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit Tim22
NCBI Official Synonym Full Names
translocase of inner mitochondrial membrane 22 homolog (yeast)
NCBI Official Symbol
TIMM22
NCBI Official Synonym Symbols
TEX4; TIM22
NCBI Protein Information
mitochondrial import inner membrane translocase subunit Tim22
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit Tim22
UniProt Gene Name
TIMM22
UniProt Synonym Gene Names
TEX4; TIM22
UniProt Entry Name
TIM22_HUMAN

Uniprot Description

TIMM22: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps. Belongs to the Tim17/Tim22/Tim23 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: integral to membrane; mitochondrial inner membrane

Molecular Function: mitochondrion targeting sequence binding; protein channel activity

Biological Process: protein import into mitochondrial inner membrane; protein targeting to mitochondrion

Research Articles on TIMM22

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Product Notes

The TIMM22 timm22 (Catalog #AAA7031252) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-194aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the TIMM22 timm22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAAAAPNAGG SAPETAGSAE APLQYSLLLQ YLVGDKRQPR LLEPGSLGGI PSPAKSEEQK MIEKAMESCA FKAALACVGG FVLGGAFGVF TAGIDTNVGF DPKDPYRTPT AKEVLKDMGQ RGMSYAKNFA IVGAMFSCTE CLIESYRGTS DWKNSVISGC ITGGAIGFRA GLKAGAIGCG GFAAFSAAID YYLR. It is sometimes possible for the material contained within the vial of "Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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