P2X receptor A (p2xA) Recombinant Protein | p2xA recombinant protein
Recombinant Dictyostelium discoideum P2X receptor A (p2xA)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
P2X receptor A (p2xA); Recombinant Dictyostelium discoideum P2X receptor A (p2xA); p2xA recombinant protein
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
1-378aa; full length protein
Sequence
MGFSFDWDDIFQYSTVKIVRIRDRRLGILHLSFLVGIVAYIVVYSAIIKKGYLFTEVPIG SVRTSLKGPNTFASNLTYCSNQQHNGSTYPFTPLECNYWDEQLALFPVGQDSTFTCTTRV RLSKQEANCNFTDPTCKFVDEPGSAKNIYIADIESFTILIDHTMYASSSGSQFNAVDLHG YILNQDGDEVQIDANGTSIGVSGKPDIMTIGQLLSFGGVSLDQASPVDSNVSIRYDGVVL FVFITYSNTYTYSTSDFKYVYSVQQIANTIYDVPETIILESIHSRLLYKRHGIRVIFIQT GTIGSFHFQTLLLTLVSGLGLLAVATTVVDQLAIRLLPQRKSYSSLKFQVTESMSNPMKK RITTDEGEDVLYTRIEGL
Sequence Length
Full length protein
Application Notes
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Species
Dictyostelium discoideum (Slime mold)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Product Categories/Family for p2xA recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,186 Da
NCBI Official Full Name
P2X receptor
NCBI Official Symbol
p2xA
NCBI Protein Information
P2X receptor; P2X receptor ATP-gated ion channel
UniProt Protein Name
P2X receptor A
Protein Family
UniProt Gene Name
p2xA
UniProt Synonym Gene Names
DdP2X; P2XA
UniProt Entry Name
P2XA_DICDI
Uniprot Description
P2X receptors are ATP-gated ion channels that play a role in intracellular calcium signaling. Not required for the purinergic response to extracellular nucleotides. Inward currents evoked by intracellular ATP and ATP analogs. Exclusively selective for ATP over other nucleotides. Insensitive to P2 receptor antagonists PPADS, suramin and 2',3'-O-(2,4,6-trinitrophenyl)-ATP but inhibited by nanomolar concentrations of copper and sodium ion. More permeable to ammonium than either sodium or potassium ions and less permeable to choline. It has been reported that p2xA is not essential for osmoregulation (PubMed:19833731), however this information is in contradiction with another source (PubMed:17625565) which indicates that p2xA is required for osmoregulation. Found to be permeable to chloride ions. Inhibited by copper and sodium ions.
Research Articles on p2xA
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Product Notes
The p2xA p2xa (Catalog #AAA7025301) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-378aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the p2xA p2xa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGFSFDWDDI FQYSTVKIVR IRDRRLGILH LSFLVGIVAY IVVYSAIIKK GYLFTEVPIG SVRTSLKGPN TFASNLTYCS NQQHNGSTYP FTPLECNYWD EQLALFPVGQ DSTFTCTTRV RLSKQEANCN FTDPTCKFVD EPGSAKNIYI ADIESFTILI DHTMYASSSG SQFNAVDLHG YILNQDGDEV QIDANGTSIG VSGKPDIMTI GQLLSFGGVS LDQASPVDSN VSIRYDGVVL FVFITYSNTY TYSTSDFKYV YSVQQIANTI YDVPETIILE SIHSRLLYKR HGIRVIFIQT GTIGSFHFQT LLLTLVSGLG LLAVATTVVD QLAIRLLPQR KSYSSLKFQV TESMSNPMKK RITTDEGEDV LYTRIEGL. It is sometimes possible for the material contained within the vial of "P2X receptor A (p2xA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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