NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Ndufa13) Recombinant Protein | Ndufa13 recombinant protein
Recombinant Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Ndufa13)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
GRIM-19: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. Defects in NDUFA13 may be a cause of susceptibility to Hurthle cell thyroid carcinoma (HCTC). Hurthle cell thyroid carcinoma accounts for approximately 3% of all thyroid cancers. Although they are classified as variants of follicular neoplasms, they are more often multifocal and somewhat more aggressive and are less likely to take up iodine than are other follicular neoplasms. Belongs to the complex I NDUFA13 subunit family.
Protein type: Mitochondrial; Oxidoreductase; Membrane protein, integral
Cellular Component: cytoplasm; mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain; mitochondrial respiratory chain complex I; mitochondrion; nucleoplasm; nucleus
Molecular Function: ATP binding; NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity
Biological Process: negative regulation of cell growth; negative regulation of transcription, DNA-dependent; positive regulation of caspase activity; positive regulation of protein catabolic process; protein import into mitochondrial inner membrane
Research Articles on Ndufa13
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Product Notes
The Ndufa13 ndufa13 (Catalog #AAA7023210) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-144aa; full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Ndufa13 ndufa13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: AASKVKQDMP PPGGYGPIDY KRNLPRRGLS GYSMFAVGIG ALIFGYWRMM RWNQERRRLL IEDLEARIAL MPLFQAEKDR RTLQILRENL EEEAIIMKDV PNWKVGESVF HTTRWVPPLI GEMYGLRTKE EMSNANFGFT WYT. It is sometimes possible for the material contained within the vial of "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (Ndufa13), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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