Rabbit anti-Human, mouse STXBP6 Polyclonal Antibody | anti-STXBP6 antibody

STXBP6 Antibody

Cat. Num. AAA7001313

• Gene Names: STXBP6; amisyn; HSPC156
• Reactivity: Human, mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified.
• Synonyms: STXBP6; Polyclonal Antibody; STXBP6 Antibody; Syntaxin-binding protein 6; Amisyn; HSPC156; anti-STXBP6 antibody

• Host: Rabbit
• Reactivity: Human, mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified.
• Form/Format: Liquid
• Sequence Length: 210

• Applicable Applications for anti-STXBP6 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Recommended dilution: ; ; WB 1:500-2000; IHC 1:20-1:200; IF 1:50-1:200
• Immunogen: Recombinant human Syntaxin-binding protein 6 protrein (2-210AA).
• Research Area: Neuroscience
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68400
• Preparation and Storage: Upon receipt store at -20°C or -80°C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: STXBP6 antibody at 2ug/ml+mouse brain tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 24,12 kDaObserved band size: 24 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS7001313 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using MBS7001313 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of Hepg2 cells using MBS7001313 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-STXBP6 antibody

Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis.

NCBI and Uniprot Product Information

• NCBI GI #: 751247010
• NCBI GeneID: 29091
• NCBI Accession #: NP_001291405.1
• NCBI GenBank Nucleotide #: NM_001304476.1
• UniProt Accession #: Q8NFX7; Q8N3H1; Q8N8D5; Q96GF3; Q9P008; D3DS78
• NCBI Official Full Name: syntaxin-binding protein 6
• NCBI Official Synonym Full Names: syntaxin binding protein 6
• NCBI Official Symbol: STXBP6
• NCBI Official Synonym Symbols: amisyn; HSPC156
• NCBI Protein Information: syntaxin-binding protein 6
• UniProt Protein Name: Syntaxin-binding protein 6
• Protein Family: Syntaxin-binding protein
• UniProt Gene Name: STXBP6
• UniProt Entry Name: STXB6_HUMAN

NCBI Description

STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]

Uniprot Description

STXBP6: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: exocyst; integral to membrane; plasma membrane

Molecular Function: GTP-Rho binding; phosphatidylinositol-4,5-bisphosphate binding

Biological Process: exocyst localization; exocytosis; Golgi to plasma membrane transport; negative regulation of exocytosis