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Testing Data

IL-17F recombinant protein

Murine IL-17F

Gene Names
Il17f; C87042; IL-17F
Reactivity
Species Reactivity: Mouse
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
IL-17F; Murine IL-17F; Recombinant Murine IL-17F; IL-17F recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Species Reactivity: Mouse
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
MRKNPKAGV PALQKAGNC PPLEDNTVR VDIRIFNQN QGISVPREF QNRSSSPWD YNITRDPHR FPSEIAEAQ CRHSGCINA QGQEDSTMN SVAIQQEIL VLRREPQGC SNSFRLEKM LLKVGCTCV KPIVHQAA
Cell Type
T Cells
Preparation and Storage
At -20 degree C

Testing Data

Testing Data
Related Product Information for IL-17F recombinant protein
IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.
Product Categories/Family for IL-17F recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17,020 Da
NCBI Official Full Name
Interleukin-17F
NCBI Official Synonym Full Names
interleukin 17F
NCBI Official Symbol
Il17f
NCBI Official Synonym Symbols
C87042; IL-17F
NCBI Protein Information
interleukin-17F
UniProt Protein Name
Interleukin-17F
UniProt Gene Name
Il17f
UniProt Synonym Gene Names
IL-17F
UniProt Entry Name
IL17F_MOUSE

Uniprot Description

IL17F: Stimulates the production of other cytokines such as IL- 6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. Belongs to the IL-17 family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Cellular Component: extracellular space; extracellular region

Molecular Function: protein homodimerization activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine binding; cytokine activity

Biological Process: proteoglycan metabolic process; negative regulation of angiogenesis; regulation of interleukin-8 biosynthetic process; regulation of transforming growth factor beta receptor signaling pathway; lymphotoxin A biosynthetic process; regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; cytokine biosynthetic process; regulation of interleukin-2 biosynthetic process; cartilage development; regulation of interleukin-6 biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; inflammatory response

Research Articles on IL-17F

Similar Products

Product Notes

The IL-17F il17f (Catalog #AAA695825) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine IL-17F reacts with Species Reactivity: Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MRKNPKAGV PALQKAGNC PPLEDNTVR VDIRIFNQN QGISVPREF QNRSSSPWD YNITRDPHR FPSEIAEAQ CRHSGCINA QGQEDSTMN SVAIQQEIL VLRREPQGC SNSFRLEKM LLKVGCTCV KPIVHQAA. It is sometimes possible for the material contained within the vial of "IL-17F, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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