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GRO-alpha/MGSA (CXCL1) active protein

Human GRO-alpha/MGSA (CXCL1)

Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Synonyms
GRO-alpha/MGSA (CXCL1); Human GRO-alpha/MGSA (CXCL1); Recombinant Human GRO/MGSA; GRO-alpha/MGSA (CXCL1) active protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE and HPLC analyses
Form/Format
Lyophilized (0.5 x PBS)
Sequence
ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKN GRKA CLNPASPIVK KIIEKMLNSD KSN
Sequence Length
73
Endotoxin Level
< 0.1 ng /ug of protein (<1EU/ug).
mRNA RefSeq
NM_001511.3
Biological Activity
Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
Preparation and Storage
Stability:
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

Reconstitution:
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Related Product Information for GRO-alpha/MGSA (CXCL1) active protein
Human GRO alpha (also known as MGSA) promotes neutrophil chemotaxis and degranulation. It also stimulates mitogenesis in certain human melanoma cells. Human GROa is a 7.8 kDa protein containing 73 amino acid residues
Product Categories/Family for GRO-alpha/MGSA (CXCL1) active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
7.8 kDa
NCBI Official Full Name
Ferredoxin
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
NCBI Official Symbol
CXCL1
NCBI Official Synonym Symbols
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
NCBI Protein Information
growth-regulated alpha protein; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha)
UniProt Protein Name
Ferredoxin
UniProt Entry Name
FER_ALIAC

NCBI Description

This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Jan 2012]

Uniprot Description

Function: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

Cofactor: Binds 1 3Fe-4S cluster

Probable.Binds 1 4Fe-4S cluster

Probable.

Sequence similarities: Contains 2 4Fe-4S ferredoxin-type domains.

Research Articles on GRO-alpha/MGSA (CXCL1)

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Product Notes

The GRO-alpha/MGSA (CXCL1) (Catalog #AAA692073) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human GRO-alpha/MGSA (CXCL1) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKN GRKA CLNPASPIVK KIIEKMLNSD KSN. It is sometimes possible for the material contained within the vial of "GRO-alpha/MGSA (CXCL1), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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