RELM alpha active protein
Mouse RELM alpha
Gene Names
Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
RELM alpha; Mouse RELM alpha; Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik; RELM alpha active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCP AGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS
Sequence Length
89
Endotoxin Level
< 0.1 ng per ug of RELM-alpha
Structural Information
Monomeric
Endotoxin level
<0.1 ng/ug of protein (<1EU/ug)
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Biological Activity
Data not available.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Related Product Information for RELM alpha active protein
RELMalpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELMalpha and RELMbeta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMalpha and Resistin are secreted exclusively by adipocytes while RELMbeta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMalpha re still unknown. Recombinant murine RELMalpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.
Product Categories/Family for RELM alpha active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10 kDa
NCBI Official Full Name
resistin-like alpha
NCBI Official Synonym Full Names
resistin like alpha
NCBI Official Symbol
Retnla
NCBI Official Synonym Symbols
HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik
NCBI Protein Information
resistin-like alpha; found in inflammatory zone 1; hypoxia-induced mitogenic factor; cysteine-rich secreted protein FIZZ1; cysteine-rich secreted protein A12-gamma; parasite-induced macrophage novel gene 1 protein
UniProt Protein Name
Resistin-like alpha
UniProt Gene Name
Retnla
UniProt Synonym Gene Names
Fizz1; Himf; Pmng1
UniProt Entry Name
RETNA_MOUSE
Uniprot Description
Function: Probable hormone. Plays a role in pulmonary vascular remodeling. Ref.7
Subunit structure: Monomer. Ref.6
Subcellular location: Secreted.
Tissue specificity: Highest levels in adipose tissue.
Sequence similarities: Belongs to the resistin/FIZZ family.
Sequence caution: The sequence BAB25104.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
Research Articles on RELM alpha
Similar Products
Product Notes
The RELM alpha retnla (Catalog #AAA691667) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse RELM alpha reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCP AGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS. It is sometimes possible for the material contained within the vial of "RELM alpha, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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