Resistin Active Protein | Retn active protein
Mouse Resistin
Gene Names
Retn; ADSF; Rstn; Xcp4; Fizz3
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC analysis
Synonyms
Resistin; Mouse Resistin; Recombinant Murine Resistin; Retn active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC analysis
Form/Format
Lyophilized
Sequence
SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLAS CPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL Q VAS
Sequence Length
114
Endotoxin Level
< 0.1 ng per ug of Resistin
Biological Activity
Data not available.
Related Product Information for Retn active protein
Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin\'s ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant murine Resistin is a 20.2 kDa disulfide-linked homodimeric protein composed of two identical 94 amino acid chains linked by a single disulfide bond.
Product Categories/Family for Retn active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20.2 kDa
NCBI Official Full Name
resistin
NCBI Official Synonym Full Names
resistin
NCBI Official Symbol
Retn
NCBI Official Synonym Symbols
ADSF; Rstn; Xcp4; Fizz3
NCBI Protein Information
resistin; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; dominant inhibitory adipocyte-specific secretory factor; adipose-specific cysteine-rich secreted protein A12-alpha
UniProt Protein Name
Resistin
Protein Family
UniProt Gene Name
Retn
UniProt Synonym Gene Names
Fizz3; ADSF
UniProt Entry Name
RETN_MOUSE
Uniprot Description
Function: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
Subunit structure: Homodimer; disulfide-linked. Ref.4 Ref.5
Subcellular location: Secreted.
Tissue specificity: Expressed in white but not brown adipose tissue in a variety of organs.
Sequence similarities: Belongs to the resistin/FIZZ family.
Research Articles on Retn
Similar Products
Product Notes
The Retn retn (Catalog #AAA691631) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse Resistin reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLAS CPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL Q VAS. It is sometimes possible for the material contained within the vial of "Resistin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
