Carboxypeptidase-B Active Protein | Cpb1 active protein
Rat Carboxypeptidase-B
Gene Names
Cpb1; Cpb
Purity
>95% by SDS-PAGE & HPLC analysis
Synonyms
Carboxypeptidase-B; Rat Carboxypeptidase-B; Cpb1; Cpb; Cpb1 active protein
Host
E. coli
Purity/Purification
>95% by SDS-PAGE & HPLC analysis
Form/Format
Lyophilized (20mM Tris, pH 8.0 + 50mM NaCl)
Sequence
ASGHSYTKYN NWETIEAWIQ QVATDNPDLV TQSVIGTTFE
GRNMYVLKIG KTRPNKPAIF IDCGFHAREW ISPAFCQWFV
REAVRTYNQE IHMKQLLDEL DFYVLPVVNI DGYVYTWTKD
RMWRKTRSTM AGSSCLGVDP NRNFNAGWCE VGASRSPCSE
TYCGPAPESE KETKALADFI RNNLSTIKAY LTIHSYSQMM
LYPYSYDYKL PENYEELNAL VKGAAKELAT LHGTKYTYGP
GATTIYPAAG GSDDWSYDQG IKYSFTFELR DTGFFGFLLP
ESQIRQTCEE TMLAVKYIAN YVREHLY
Endotoxin level
< 0.1 ng /ug of protein (<1EU/ug).
Length (aa)
307
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer (e.g. PBS) containing a carrier protein (e.g. 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Biological Activity
Carboxypeptidase-B sequentially cleaves C terminal K and R residues.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Related Product Information for Cpb1 active protein
Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Carboxypeptidase-B sequentially cleaves C terminal K and R residues. Recombinant rat Carboxypeptidase-B is a 35.1 kDa protein consisting of 307 amino acids.
Product Categories/Family for Cpb1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,515 Da
NCBI Official Full Name
carboxypeptidase B
NCBI Official Synonym Full Names
carboxypeptidase B1 (tissue)
NCBI Official Symbol
Cpb1
NCBI Official Synonym Symbols
Cpb
NCBI Protein Information
carboxypeptidase B; pancreatic carboxypeptidase B1
UniProt Protein Name
Carboxypeptidase B
UniProt Gene Name
Cpb1
UniProt Synonym Gene Names
Cpb
UniProt Entry Name
CBPB1_RAT
NCBI Description
putative carboxypeptidase B protein [RGD, Feb 2006]
Uniprot Description
Catalytic activity: Preferential release of a C-terminal lysine or arginine amino acid.
Cofactor: Binds 1 zinc ion per subunit
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the peptidase M14 family.
Research Articles on Cpb1
Similar Products
Product Notes
The Cpb1 cpb1 (Catalog #AAA691474) is an Active Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ASGHSYTKYN NWETIEAWIQ QVATDNPDLV TQSVIGTTFE GRNMYVLK IG KTRPNKPAIF IDCGFHAREW ISPAFCQWFV REAVRTYN QE IHMKQLLDEL DFYVLPVVNI DGYVYTWTKD RMWRKTRS TM AGSSCLGVDP NRNFNAGWCE VGASRSPCSE TYCGPAPE SE KETKALADFI RNNLSTIKAY LTIHSYSQMM LYPYSYDY KL PENYEELNAL VKGAAKELAT LHGTKYTYGP GATTIYPA AG GSDDWSYDQG IKYSFTFELR DTGFFGFLLP ESQIRQTC EE TMLAVKYIAN YVREHLY. It is sometimes possible for the material contained within the vial of "Carboxypeptidase-B, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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