Hamster Aldehyde Dehydrogenase 3 Family, Member A1 ELISA Kit | ALDH3A1 elisa kit
Hamster Aldehyde Dehydrogenase 3 Family, Member A1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]
Uniprot Description
ALDH8A1: Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). Belongs to the aldehyde dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.2.1.-; Oxidoreductase
Chromosomal Location of Human Ortholog: 6q23.2
Cellular Component: cytoplasm; intracellular
Molecular Function: aldehyde dehydrogenase (NAD) activity; retinal dehydrogenase activity
Biological Process: retinal metabolic process; 9-cis-retinoic acid biosynthetic process; retinoic acid metabolic process
Research Articles on ALDH3A1
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Product Notes
The Hamster ALDH3A1 aldh8a1 (Catalog #AAA068462) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA068462 ELISA Kit recognizes Hamster ALDH3A1. It is sometimes possible for the material contained within the vial of "Aldehyde Dehydrogenase 3 Family, Member A1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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