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Borrelidin Antibiotic | borA6 antibiotic

Borrelidin (Treponemycin, Antibiotic U 78548, Antibiotic C2989)

Purity
Highly Purified
>99% by HPLC
Synonyms
Borrelidin; Borrelidin (Treponemycin; Antibiotic U 78548; Antibiotic C2989); borA6 antibiotic
Ordering
For Research Use Only!
Host
Streptomyces sp
Purity/Purification
Highly Purified
>99% by HPLC
CAS Number
7184-60-3
Molecular Formula
C28H43NO6
Solubility
Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO.
Preparation and Storage
-20 degree C
Related Product Information for borA6 antibiotic
Borrelidin is an unusual nitrile containing metabolite isolated from Streptomyces. Originally discovered as active against against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery displaying activity against drug-resistant Plasmodia.
Product Categories/Family for borA6 antibiotic

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
489.64
NCBI Official Full Name
Borrelidin polyketide synthase, type I
UniProt Protein Name
Borrelidin polyketide synthase, type I
UniProt Gene Name
borA6
UniProt Entry Name
Q70HZ7_9ACTO

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Product Notes

The Borrelidin bora6 (Catalog #AAA651415) is an Antibiotic produced from Streptomyces sp and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Borrelidin, Antibiotic" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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